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NANOGP8: Evolution of a Human-Specific Retro-Oncogene

NANOGP8 is a human (Homo sapiens) retrogene, expressed predominantly in cancer cells where its protein product is tumorigenic. It arose through retrotransposition from its parent gene, NANOG, which is expressed predominantly in embryonic stem cells. Based on identification of fixed and polymorphic v...

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Detalles Bibliográficos
Autores principales: Fairbanks, Daniel J., Fairbanks, Aaron D., Ogden, T. Heath, Parker, Glendon J., Maughan, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484675/
https://www.ncbi.nlm.nih.gov/pubmed/23173096
http://dx.doi.org/10.1534/g3.112.004366