Cargando…

NANOGP8: Evolution of a Human-Specific Retro-Oncogene

NANOGP8 is a human (Homo sapiens) retrogene, expressed predominantly in cancer cells where its protein product is tumorigenic. It arose through retrotransposition from its parent gene, NANOG, which is expressed predominantly in embryonic stem cells. Based on identification of fixed and polymorphic v...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fairbanks, Daniel J., Fairbanks, Aaron D., Ogden, T. Heath, Parker, Glendon J., Maughan, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2012
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484675/ https://www.ncbi.nlm.nih.gov/pubmed/23173096 http://dx.doi.org/10.1534/g3.112.004366

Ejemplares similares

Evolution of the NANOG pseudogene family in the human and chimpanzee genomes
por: Fairbanks, Daniel J, et al.
Publicado: (2006)

Analysis of regulatory sequences in exosomal DNA of NANOGP8
por: Vaidya, Manjusha, et al.
Publicado: (2023)

In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals
por: Badeaux, Mark A, et al.
Publicado: (2013)

NANOG/NANOGP8 Localizes at the Centrosome and is Spatiotemporally Associated with Centriole Maturation
por: Mikulenkova, Erika, et al.
Publicado: (2020)

Targeting the somatosensory system with AAV9 and AAV2retro viral vectors
por: Skorput, Alexander G. J., et al.
Publicado: (2022)

Oncogenic NanogP8 expression regulates cell proliferation and migration through the Akt/mTOR signaling pathway in human gastric cancer – SGC-7901cell line
por: Jiang, Zheng, et al.
Publicado: (2016)

CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells
por: Kawamura, Norihiko, et al.
Publicado: (2015)

NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cells
por: Ma, Xia, et al.
Publicado: (2018)

Roles of NANOGP8 in cancer metastasis and cancer stem cell invasion during development of castration-resistant prostate cancer
por: Sui, Yi, et al.
Publicado: (2021)

Mendel and Darwin: untangling a persistent enigma
por: Fairbanks, Daniel J.
Publicado: (2019)

NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naïve pluripotent stem cells
por: Maskalenka, Katsiaryna, et al.
Publicado: (2023)

Endothelial cells activate the cancer stem cell‐associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion
por: Wang, Rui, et al.
Publicado: (2017)

Maternal Effects in Ontogeny and Evolution: Maternal Effects in Mammals. Edited by Dario Maestripieri and Jill M. Mateo. Chicago: University of Chicago Press. 2009. 360 pp., $90.00 (cloth). ISBN 978-0-226-50119-2
por: Fairbanks, Lynn A.
Publicado: (2009)

Synthetic and semi-synthetic approaches to unprotected N-glycan oxazolines
por: Fairbanks, Antony J
Publicado: (2018)

Meet the Board of ChemistryOpen: Antony J. Fairbanks
por: Fairbanks, Antony J.
Publicado: (2019)

Virtual Issue: Carbohydrates in the 21(st) Century: Synthesis and Applications
por: Fairbanks, Antony J.
Publicado: (2015)

Experiments on Plant Hybrids by Gregor Mendel
por: Abbott, Scott, et al.
Publicado: (2016)

Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model
por: Liu, Bigang, et al.
Publicado: (2017)

Just enough software architecture /
por: Fairbanks, George
Publicado: (2012)

The Treatment of Dislocation of the Head of the Humerus
por: Fairbanks, W.
Publicado: (1887)

Obstetric Practice in Rural Districts: A Register, with Notes
por: Fairbanks, Wm.
Publicado: (1887)

The Use of the Aspirator in Retention of Urine
por: Fairbanks, W.
Publicado: (1886)

Selective anomeric acetylation of unprotected sugars in water
por: Lim, David, et al.
Publicado: (2017)

Role of Conformational Dynamics in the Evolution of Retro-Aldolase Activity
por: Romero-Rivera, Adrian, et al.
Publicado: (2017)

Characterization of Angle Accuracy and Precision of 3-Degree-of-Freedom Absolute Encoder Based on NanoGPS OxyO Technology
por: Pisani, Marco, et al.
Publicado: (2020)

Retro-Ocular Neuritis
por: Shorten, J. H.
Publicado: (1910)

Search for the $B_{c}$ meson in hadronic $Z^{0}$ decays using the OPAL detector at LEP
por: Herndon, Matthew Fairbanks
Publicado: (1999)

Nanog1 in NTERA-2 and Recombinant NanogP8 from Somatic Cancer Cells Adopt Multiple Protein Conformations and Migrate at Multiple M.W Species
por: Liu, Bigang, et al.
Publicado: (2014)

The Evolution and Consequences of Sex-Specific Reproductive Variance
por: Mullon, Charles, et al.
Publicado: (2014)

IL‐12 and IL‐4 activate a CD39‐dependent intrinsic peripheral tolerance mechanism in CD8(+) T cells
por: Noble, Alistair, et al.
Publicado: (2016)

Papillomaviruses Go Retro
por: Xie, Jian, et al.
Publicado: (2020)

LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1
por: Wang, Bei, et al.
Publicado: (2016)

Pocket guide to antimicrobial therapy in otolaryngology: head and neck surgery /
por: Fairbanks, David N. F.
Publicado: (1996)

Modern retro /
por: Bingham, Neil R.
Publicado: (2000)

Genome Size Evolution Differs Between Drosophila Subgenera with Striking Differences in Male and Female Genome Size in Sophophora
por: Hjelmen, Carl E., et al.
Publicado: (2019)

Tissue-Specific Transcriptome for Poeciliopsis prolifica Reveals Evidence for Genetic Adaptation Related to the Evolution of a Placental Fish
por: Jue, Nathaniel K., et al.
Publicado: (2018)

Evolution of a designed retro-aldolase leads to complete active site remodeling
por: Giger, Lars, et al.
Publicado: (2013)

Endogenous Retrovirus Insertion in the KIT Oncogene Determines White and White spotting in Domestic Cats
por: David, Victor A., et al.
Publicado: (2014)

Experimental Evolution Reveals Favored Adaptive Routes to Cell Aggregation in Yeast
por: Hope, Elyse A., et al.
Publicado: (2017)

The Evolution of Gene-Specific Transcriptional Noise Is Driven by Selection at the Pathway Level
por: Barroso, Gustavo Valadares, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_efnk72o794dl61elr098k1ch5s