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Understanding the hypoxic niche of multiple myeloma: therapeutic implications and contributions of mouse models

Multiple myeloma (MM) is the second most common hematological malignancy and is characterized by the clonal expansion of plasma cells in the bone marrow. Recently, hypoxia has received increased interest in the context of MM, in both basic and translational research. In this review, we describe the...

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Detalles Bibliográficos
Autores principales: Hu, Jinsong, Van Valckenborgh, Els, Menu, Eline, De Bruyne, Elke, Vanderkerken, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484859/
https://www.ncbi.nlm.nih.gov/pubmed/23115205
http://dx.doi.org/10.1242/dmm.008961