Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

The availability of animal models of epileptic seizures provides opportunities to identify novel anticonvulsants for the treatment of people with epilepsy. We found that exposure of 2-day-old zebrafish embryos to the convulsant agent pentylenetetrazole (PTZ) rapidly induces the expression of synapti...

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Detalles Bibliográficos
Autores principales: Baxendale, Sarah, Holdsworth, Celia J., Meza Santoscoy, Paola L., Harrison, Michael R. M., Fox, James, Parkin, Caroline A., Ingham, Philip W., Cunliffe, Vincent T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484860/
https://www.ncbi.nlm.nih.gov/pubmed/22730455
http://dx.doi.org/10.1242/dmm.010090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484860/
https://www.ncbi.nlm.nih.gov/pubmed/22730455
http://dx.doi.org/10.1242/dmm.010090

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