Cargando…

Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures

The availability of animal models of epileptic seizures provides opportunities to identify novel anticonvulsants for the treatment of people with epilepsy. We found that exposure of 2-day-old zebrafish embryos to the convulsant agent pentylenetetrazole (PTZ) rapidly induces the expression of synapti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baxendale, Sarah, Holdsworth, Celia J., Meza Santoscoy, Paola L., Harrison, Michael R. M., Fox, James, Parkin, Caroline A., Ingham, Philip W., Cunliffe, Vincent T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Limited 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484860/ https://www.ncbi.nlm.nih.gov/pubmed/22730455 http://dx.doi.org/10.1242/dmm.010090

Ejemplares similares

Immune Profile in Blood Following Non-convulsive Epileptic Seizures in Rats
por: Avdic, Una, et al.
Publicado: (2019)

Adaptive Remote Sensing Paradigm for Real-Time Alerting of Convulsive Epileptic Seizures
por: Kalitzin, Stiliyan
Publicado: (2023)

Imaging Neuronal Activity in the Optic Tectum of Late Stage Larval Zebrafish
por: Bergmann, Katharina, et al.
Publicado: (2018)

Convulsive seizures and SUDEP in a mouse model of SCN8A epileptic encephalopathy
por: Wagnon, Jacy L., et al.
Publicado: (2015)

Case of Puerperal Epileptic Convulsions
por: Low, Wm. Cook
Publicado: (1861)

Convulsive Seizures
por: Kahn, Eugen
Publicado: (1943)

Convulsive Syncope Induced by Ventricular Arrhythmia Masquerading as Epileptic Seizures: Case Report and Literature Review
por: Sabu, John, et al.
Publicado: (2016)

Non-Epileptic Convulsions in Growing Children
Publicado: (1903)

Eclampsia—Purperal Convulsions: Variety, Epileptic
por: Payne, Alban S.
Publicado: (1872)

A comparison of the cost-effectiveness of treatment of prolonged acute convulsive epileptic seizures in children across Europe
por: Lee, Dawn C, et al.
Publicado: (2014)

Evaluation of Anti-Convulsive Properties of Aqueous Kava Extract on Zebrafish Using the PTZ-Induced Seizure Model
por: Jaiswal, Yogini, et al.
Publicado: (2020)

Epileptic seizures
por: Anwar, Haleema, et al.
Publicado: (2020)

Prevalence and mortality of epilepsies with convulsive and non-convulsive seizures in Kilifi, Kenya
por: Kariuki, Symon M, et al.
Publicado: (2021)

Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant
por: Diamantopoulou, Elvira, et al.
Publicado: (2019)

Volumetric optoacoustic neurobehavioral tracking of epileptic seizures in freely-swimming zebrafish larvae
por: Özsoy, Çağla, et al.
Publicado: (2022)

Akinetopsia as epileptic seizure()
por: Sakurai, Kotaro, et al.
Publicado: (2013)

Simultaneous posterior fracture dislocation of the shoulder following epileptic convulsion
por: Jansen, Hendrik, et al.
Publicado: (2012)

The role of Sox6 in zebrafish muscle fiber type specification
por: Jackson, Harriet E, et al.
Publicado: (2015)

A novel metabolism-based phenotypic drug discovery platform in zebrafish uncovers HDACs 1 and 3 as a potential combined anti-seizure drug target
por: Ibhazehiebo, Kingsley, et al.
Publicado: (2018)

Predicting Epileptic Seizures in Advance
por: Moghim, Negin, et al.
Publicado: (2014)

Epileptic seizure? Certainly uncertain
por: Heinrich, Sven P., et al.
Publicado: (2021)

Postoperative Epileptic Seizures in Children
por: Massimi, Luca, et al.
Publicado: (2022)

Late Seizures after Stroke in Clinical Practice: The Prevalence of Non-convulsive Seizures
por: Miyaji, Yosuke, et al.
Publicado: (2017)

Febrile seizures and convulsions with mild gastroenteritis: age-dependent acute symptomatic seizures
por: Cappellari, Alberto M., et al.
Publicado: (2023)

Nicotine Elicits Convulsive Seizures by Activating Amygdalar Neurons
por: Iha, Higor A., et al.
Publicado: (2017)

Non-convulsive seizure clustering misdiagnosed as vertebrobasilar insufficiency
por: Chen, Yu-Shiue, et al.
Publicado: (2020)

Dementia with non-convulsive seizures: a case report
por: Chen, Yu-Shiue, et al.
Publicado: (2021)

Predictors of anti-convulsant treatment failure in children presenting with malaria and prolonged seizures in Kampala, Uganda
por: Mpimbaza, Arthur, et al.
Publicado: (2009)

Proteomic Analysis of patients with Epileptic Seizure and Psychogenic Non-epileptic Seizure; a Cross-Sectional Study
por: Parvareshi Hamrah, Mohsen, et al.
Publicado: (2020)

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish
por: Zhang, Yifan, et al.
Publicado: (2017)

Drug screening: zebrafish as a tool for studying epileptic-related chemical compounds
por: Zhao, Sha-Sha, et al.
Publicado: (2015)

Zebrafish larvae exposed to ginkgotoxin exhibit seizure-like behavior that is relieved by pyridoxal-5′-phosphate, GABA and anti-epileptic drugs
por: Lee, Gang-Hui, et al.
Publicado: (2012)

Epileptic seizure after treatment with thiocolchicoside
por: Giavina-Bianchi, Pedro, et al.
Publicado: (2009)

Analysis of Epileptic Seizures with Complex Network
por: Ni, Yan, et al.
Publicado: (2014)

Nonketotic hyperglycemia-related epileptic seizures()
por: Wang, Xuejian, et al.
Publicado: (2013)

Correction: Predicting Epileptic Seizures in Advance
Publicado: (2015)

Epileptic Seizure, Postictal Hemiparesis, and Hyperleukocytosis
por: Olivieri, Martin, et al.
Publicado: (2016)

Epileptic Seizure Due to Disulfiram Treatment
por: Erensoy, Habib, et al.
Publicado: (2019)

Cardiac Arrhythmia Following an Epileptic Seizure
por: Kuttab, Hani I., et al.
Publicado: (2019)

Epileptic seizures triggered by eating in dogs
por: Brocal, Josep, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2i1k9a3vl12hca32omvmgrf6b3