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Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology

Subarachnoid haemorrhage (SAH) is a major contributor to the burden of stroke on society. Treatment options are limited and animal models of SAH do not always mimic key pathophysiological hallmarks of the disease, thus hindering development of new therapeutics. Inflammation is strongly associated wi...

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Detalles Bibliográficos
Autores principales: Greenhalgh, Andrew D., Brough, David, Robinson, Emily M., Girard, Sylvie, Rothwell, Nancy J., Allan, Stuart M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484865/
https://www.ncbi.nlm.nih.gov/pubmed/22679224
http://dx.doi.org/10.1242/dmm.008557