Cargando…

Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology

Subarachnoid haemorrhage (SAH) is a major contributor to the burden of stroke on society. Treatment options are limited and animal models of SAH do not always mimic key pathophysiological hallmarks of the disease, thus hindering development of new therapeutics. Inflammation is strongly associated wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Greenhalgh, Andrew D., Brough, David, Robinson, Emily M., Girard, Sylvie, Rothwell, Nancy J., Allan, Stuart M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Limited 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484865/ https://www.ncbi.nlm.nih.gov/pubmed/22679224 http://dx.doi.org/10.1242/dmm.008557

Ejemplares similares

The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial
por: Singh, Navneet, et al.
Publicado: (2014)

The role of cortisol in immunosuppression in subarachnoid haemorrhage
por: Hoadley, Margaret E., et al.
Publicado: (2023)

Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection
por: Hopkins, Stephen J, et al.
Publicado: (2012)

Beneficial Effect of Sodium Nitrite on EEG Ischaemic Markers in Patients with Subarachnoid Haemorrhage
por: Luettich, Alexander, et al.
Publicado: (2021)

SUBARACHNOID HÆMORRHAGE
Publicado: (1956)

Microglia and Macrophages Differentially Modulate Cell Death After Brain Injury Caused by Oxygen-Glucose Deprivation in Organotypic Brain Slices
por: Girard, Sylvie, et al.
Publicado: (2013)

Haem-driven IL-1 in acute brain injury
Publicado: (2012)

Familial subarachnoid haemorrhage.
por: Bailey, I. C.
Publicado: (1993)

Subarachnoid Haemorrhage and Sports
por: Sousa Nanji, Liliana, et al.
Publicado: (2015)

Spontaneous Subarachnoid Hæmorrhage
por: Menon, C. K.
Publicado: (1939)

Spontaneous Subarachnoid Hæmorrhage
por: Chaudhuri, R. N.
Publicado: (1938)

Spontaneous Subarachnoid Hæmorrhage
por: Patrick, Adam
Publicado: (1933)

The Pathology of Subarachnoid Haemorrhage
por: Crompton, M. Rufus
Publicado: (1973)

Aneurysmatic subarachnoid haemorrhage
por: Onur, Oezguer A., et al.
Publicado: (2019)

Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage
por: McMahon, Catherine J, et al.
Publicado: (2013)

The Dynamics and Mechanisms of Interleukin-1α and β Nuclear Import
por: Luheshi, Nadia M, et al.
Publicado: (2008)

Haem-responsive gene transporter enables mobilization of host haem in ticks
por: Perner, J., et al.
Publicado: (2021)

Dual functionality of interleukin-1 family cytokines: implications for anti-interleukin-1 therapy
por: Luheshi, NM, et al.
Publicado: (2009)

Traumatic subarachnoid haemorrhage in the ICU
por: Pérez, M González, et al.
Publicado: (2006)

Outcomes from subarachnoid haemorrhage
por: Whitehead, I, et al.
Publicado: (2009)

Medical Aspects of Subarachnoid Haemorrhage
por: Gautier-Smith, P. C.
Publicado: (1973)

Surgical Management of Subarachnoid Haemorrhage
por: Richardson, Alan
Publicado: (1973)

Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death
por: England, Hazel, et al.
Publicado: (2014)

Heparin: Multifocal intracerebral haemorrhage and subarachnoid haemorrhage: case report
Publicado: (2021)

Predictive validity of the prognosis on admission aneurysmal subarachnoid haemorrhage scale for the outcome of patients with aneurysmal subarachnoid haemorrhage
por: Nguyen, Tuan Anh, et al.
Publicado: (2023)

Coarctation of the Aorta and Subarachnoid Hæmorrhage with Recovery
por: Marshall, Robert, et al.
Publicado: (1950)

Takotsubo cardiomyopathy in aneurysmal subarachnoid haemorrhage
por: Bhatnagar, Vidhu, et al.
Publicado: (2014)

The autophagy–lysosomal system in subarachnoid haemorrhage
por: Wu, Haijian, et al.
Publicado: (2016)

Microglial heterogeneity after subarachnoid haemorrhage
por: Galea, Ian
Publicado: (2022)

Essential histidine pairs indicate conserved haem binding in epsilonproteobacterial cytochrome c haem lyases
por: Kern, Melanie, et al.
Publicado: (2010)

Association between Haem and Non-Haem Iron Intake and Serum Ferritin in Healthy Young Women
por: Young, Isabel, et al.
Publicado: (2018)

A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke
por: Maysami, Samaneh, et al.
Publicado: (2015)

The Genetics of Primary Haemorrhagic Stroke, Subarachnoid Haemorrhage and Ruptured Intracranial Aneurysms in Adults
por: Peck, George, et al.
Publicado: (2008)

Retinal Hæmorrhages as a Diagnostic Feature in Fracture of the Base of the Skull and in Subarachnoid Hæmorrhage
por: Fleming, R. A.
Publicado: (1903)

Retinal Hæmorrhages as a Diagnostic Feature in Fracture of the Base of the Skull and in Subarachnoid Hæmorrhage
por: Fleming, R. A.
Publicado: (1903)

Intracranial pressure monitoring in patients with subarachnoid haemorrhage
por: Cormio, M, et al.
Publicado: (2001)

To Look Beyond Vasospasm in Aneurysmal Subarachnoid Haemorrhage
por: Cossu, Giulia, et al.
Publicado: (2014)

Neurofibromatosis type 1 is not associated with subarachnoid haemorrhage
por: Kurtelius, Arttu, et al.
Publicado: (2017)

Non-aneurysmal subarachnoid haemorrhage in COVID-19
por: Harrogate, Suzanne, et al.
Publicado: (2020)

CSF Proteomics of Patients with Hydrocephalus and Subarachnoid Haemorrhage
por: Sokół, Bartosz, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p4nfbep44s8efbh2dnhketpqjl