Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development

Neurofibromatosis type 1 (NF1) is a common, dominantly inherited genetic disorder that results from mutations in the neurofibromin 1 (NF1) gene. Affected individuals demonstrate abnormalities in neural-crest-derived tissues that include hyperpigmented skin lesions and benign peripheral nerve sheath...

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Detalles Bibliográficos
Autores principales: Shin, Jimann, Padmanabhan, Arun, de Groh, Eric D., Lee, Jeong-Soo, Haidar, Sam, Dahlberg, Suzanne, Guo, Feng, He, Shuning, Wolman, Marc A., Granato, Michael, Lawson, Nathan D., Wolfe, Scot A., Kim, Seok-Hyung, Solnica-Krezel, Lilianna, Kanki, John P., Ligon, Keith L., Epstein, Jonathan A., Look, A. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484870/
https://www.ncbi.nlm.nih.gov/pubmed/22773753
http://dx.doi.org/10.1242/dmm.009779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484870/
https://www.ncbi.nlm.nih.gov/pubmed/22773753
http://dx.doi.org/10.1242/dmm.009779

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