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Reduced bone morphogenetic protein receptor type 1A signaling in neural-crest-derived cells causes facial dysmorphism

Bone morphogenetic protein (BMP) receptor type 1A (BMPR1A) mutations are associated with facial dysmorphism, which is one of the main clinical signs in both juvenile polyposis and chromosome 10q23 deletion syndromes. Craniofacial development requires reciprocal epithelial/neural crest (NC)-derived m...

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Detalles Bibliográficos
Autores principales: Saito, Hiromitsu, Yamamura, Ken-ichi, Suzuki, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484876/
https://www.ncbi.nlm.nih.gov/pubmed/22773757
http://dx.doi.org/10.1242/dmm.009274