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Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice
Extracellular signals in development, physiology, homeostasis and disease often act by regulating transcription. Herein we describe a general method and specific resources for determining where and when such signaling occurs in live animals and for systematically comparing the timing and extent of d...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484877/ https://www.ncbi.nlm.nih.gov/pubmed/22888097 http://dx.doi.org/10.1242/dmm.009696 |