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Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice

Extracellular signals in development, physiology, homeostasis and disease often act by regulating transcription. Herein we describe a general method and specific resources for determining where and when such signaling occurs in live animals and for systematically comparing the timing and extent of d...

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Detalles Bibliográficos
Autores principales: Serup, Palle, Gustavsen, Carsten, Klein, Tino, Potter, Leah A., Lin, Robert, Mullapudi, Nandita, Wandzioch, Ewa, Hines, Angela, Davis, Ashley, Bruun, Christine, Engberg, Nina, Petersen, Dorthe R., Peterslund, Janny M. L., MacDonald, Raymond J., Grapin-Botton, Anne, Magnuson, Mark A., Zaret, Kenneth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484877/
https://www.ncbi.nlm.nih.gov/pubmed/22888097
http://dx.doi.org/10.1242/dmm.009696