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2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

BACKGROUND: 2-Hydroxyoleic acid is a synthetic fatty acid with potent anti-cancer activity which does not induce undesired side effects. However, the molecular and cellular mechanisms by which this compound selectively kills human glioma cancer cells without killing normal cells is not fully underst...

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Detalles Bibliográficos
Autores principales: Marcilla-Etxenike, Amaia, Martín, Maria Laura, Noguera-Salvà, Maria Antònia, García-Verdugo, José Manuel, Soriano-Navarro, Mario, Dey, Indranil, Escribá, Pablo V., Busquets, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484997/
https://www.ncbi.nlm.nih.gov/pubmed/23133576
http://dx.doi.org/10.1371/journal.pone.0048235