Cargando…
2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines
BACKGROUND: 2-Hydroxyoleic acid is a synthetic fatty acid with potent anti-cancer activity which does not induce undesired side effects. However, the molecular and cellular mechanisms by which this compound selectively kills human glioma cancer cells without killing normal cells is not fully underst...
Autores principales: | Marcilla-Etxenike, Amaia, Martín, Maria Laura, Noguera-Salvà, Maria Antònia, García-Verdugo, José Manuel, Soriano-Navarro, Mario, Dey, Indranil, Escribá, Pablo V., Busquets, Xavier |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484997/ https://www.ncbi.nlm.nih.gov/pubmed/23133576 http://dx.doi.org/10.1371/journal.pone.0048235 |
Ejemplares similares
-
Sustained activation of sphingomyelin synthase by 2-hydroxyoleic acid induces sphingolipidosis in tumor cells(1)
por: Martin, Maria Laura, et al.
Publicado: (2013) -
Treatment with albumin-hydroxyoleic acid complex restores sensorimotor function in rats with spinal cord injury: Efficacy and gene expression regulation
por: Avila-Martin, Gerardo, et al.
Publicado: (2017) -
Minerval (2-hydroxyoleic acid) causes cancer cell selective toxicity by uncoupling oxidative phosphorylation and compromising bioenergetic compensation capacity
por: Massalha, Wessal, et al.
Publicado: (2019) -
2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles
por: Antoniou, Antonia I., et al.
Publicado: (2023) -
The anti-tumor drug 2-hydroxyoleic acid (Minerval) stimulates signaling and retrograde transport
por: Torgersen, Maria L., et al.
Publicado: (2016)