Detection of Long Non-Coding RNA in Archival Tissue: Correlation with Polycomb Protein Expression in Primary and Metastatic Breast Carcinoma

A major function of long non-coding RNAs (lncRNAs) is regulating gene expression through changes in chromatin state. Experimental evidence suggests that in cancer, they can influence Polycomb Repressive Complexes (PRC) to retarget to an occupancy pattern resembling that of the embryonic state. We ha...

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Detalles Bibliográficos
Autores principales: Chisholm, Karen M., Wan, Yue, Li, Rui, Montgomery, Kelli D., Chang, Howard Y., West, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485022/
https://www.ncbi.nlm.nih.gov/pubmed/23133536
http://dx.doi.org/10.1371/journal.pone.0047998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485022/
https://www.ncbi.nlm.nih.gov/pubmed/23133536
http://dx.doi.org/10.1371/journal.pone.0047998

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