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Analysis of an Ordered, Comprehensive STM Mutant Library in Infectious Borrelia burgdorferi: Insights into the Genes Required for Mouse Infectivity

The identification of genes important in the pathogenesis of Lyme disease Borrelia has been hampered by exceedingly low transformation rates in low-passage, infectious organisms. Using the infectious, moderately transformable B. burgdorferi derivative 5A18NP1 and signature-tagged versions of the Him...

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Detalles Bibliográficos
Autores principales: Lin, Tao, Gao, Lihui, Zhang, Chuhua, Odeh, Evelyn, Jacobs, Mary B., Coutte, Loïc, Chaconas, George, Philipp, Mario T., Norris, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485029/
https://www.ncbi.nlm.nih.gov/pubmed/23133514
http://dx.doi.org/10.1371/journal.pone.0047532