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Preferential Release of Newly Synthesized Insulin Assessed by a Multi-Label Reporter System Using Pancreatic β-Cell Line MIN6

Newly synthesized hormones have been suggested to be preferentially secreted by various neuroendocrine cells. This observation indicates that there is a distinct population of secretory granules containing new and old hormones. Recent development of fluorescent timer proteins used in bovine adrenal...

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Detalles Bibliográficos
Autores principales: Hou, Ni, Mogami, Hideo, Kubota-Murata, Chisato, Sun, Meng, Takeuchi, Toshiyuki, Torii, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485036/
https://www.ncbi.nlm.nih.gov/pubmed/23133529
http://dx.doi.org/10.1371/journal.pone.0047921