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Interleukin 12 receptor deficiency in a child with recurrent bronchopneumonia and very high IgE levels
Interleukin-12 (IL-12) is involved in cellular immune responses against intracellular pathogens by promoting the generation of T naive in T helper 1 (Th1) cells and by increasing interferon-gamma (IFN-gamma) production from T and natural killer (NK) cells. A defective induction of a Th1 response may...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485094/ https://www.ncbi.nlm.nih.gov/pubmed/22992471 http://dx.doi.org/10.1186/1824-7288-38-46 |