A Δ38 Deletion Variant of Human Transketolase as a Model of Transketolase-Like Protein 1 Exhibits No Enzymatic Activity

Besides transketolase (TKT), a thiamin-dependent enzyme of the pentose phosphate pathway, the human genome encodes for two closely related transketolase-like proteins, which share a high sequence identity with TKT. Transketolase-like protein 1 (TKTL1) has been implicated in cancerogenesis as its cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider, Stefan, Lüdtke, Stefan, Schröder-Tittmann, Kathrin, Wechsler, Cindy, Meyer, Danilo, Tittmann, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485151/
https://www.ncbi.nlm.nih.gov/pubmed/23118983
http://dx.doi.org/10.1371/journal.pone.0048321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485151/
https://www.ncbi.nlm.nih.gov/pubmed/23118983
http://dx.doi.org/10.1371/journal.pone.0048321

Ejemplares similares