Encapsulation of Alpha-1 antitrypsin in PLGA nanoparticles: In Vitro characterization as an effective aerosol formulation in pulmonary diseases

BACKGROUND: Alpha 1- antitrypsin (α1AT) belongs to the superfamily of serpins and inhibits different proteases. α1AT protects the lung from cellular inflammatory enzymes. In the absence of α1AT, the degradation of lung tissue results to pulmonary complications. The pulmonary route is a potent noninv...

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Detalles Bibliográficos
Autores principales: Pirooznia, Nazanin, Hasannia, Sadegh, Lotfi, Abbas Sahebghadam, Ghanei, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485170/
https://www.ncbi.nlm.nih.gov/pubmed/22607686
http://dx.doi.org/10.1186/1477-3155-10-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485170/
https://www.ncbi.nlm.nih.gov/pubmed/22607686
http://dx.doi.org/10.1186/1477-3155-10-20

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