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Increased cellular immune responses and CD4+ T-cell proliferation correlate with reduced plasma viral load in SIV challenged recombinant simian varicella virus - simian immunodeficiency virus (rSVV-SIV) vaccinated rhesus macaques

BACKGROUND: An effective AIDS vaccine remains one of the highest priorities in HIV-research. Our recent study showed that vaccination of rhesus macaques with recombinant simian varicella virus (rSVV) vector – simian immunodeficiency virus (SIV) envelope and gag genes, induced neutralizing antibodies...

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Detalles Bibliográficos
Autores principales: Pahar, Bapi, Gray, Wayne L, Phelps, Kimberly, Didier, Elizabeth S, deHaro, Eileen, Marx, Preston A, Traina-Dorge, Vicki L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485174/
https://www.ncbi.nlm.nih.gov/pubmed/22889373
http://dx.doi.org/10.1186/1743-422X-9-160