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Covalent NEDD8 Conjugation Increases RCAN1 Protein Stability and Potentiates Its Inhibitory Action on Calcineurin

Similar to ubiquitin, regulatory roles for NEDD8 (neural precursor cell-expressed developmentally down-regulated 8) are being clarified during cell growth, signal transduction, immune response, and development. However, NEDD8 targets and their functional alterations are not well known. Regulator of...

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Detalles Bibliográficos
Autores principales: Noh, Eun Hye, Hwang, Hee Sook, Hwang, Hee Sun, Min, Boram, Im, Eunju, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485183/
https://www.ncbi.nlm.nih.gov/pubmed/23118980
http://dx.doi.org/10.1371/journal.pone.0048315