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Dynamic Hubs Show Competitive and Static Hubs Non-Competitive Regulation of Their Interaction Partners

Date hub proteins have 1 or 2 interaction interfaces but many interaction partners. This raises the question of whether all partner proteins compete for the interaction interface of the hub or if the cell carefully regulates aspects of this process? Here, we have used real-time rendering of protein...

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Detalles Bibliográficos
Autores principales: Goel, Apurv, Wilkins, Marc R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485199/
https://www.ncbi.nlm.nih.gov/pubmed/23118954
http://dx.doi.org/10.1371/journal.pone.0048209