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Integrative Binding Sites within Intracellular Termini of TRPV1 Receptor

TRPV1 is a nonselective cation channel that integrates wide range of painful stimuli. It has been shown that its activity could be modulated by intracellular ligands PIP2 or calmodulin (CaM). The detailed localization and description of PIP2 interaction sites remain unclear. Here, we used synthesize...

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Detalles Bibliográficos
Autores principales: Grycova, Lenka, Holendova, Blanka, Bumba, Ladislav, Bily, Jan, Jirku, Michaela, Lansky, Zdenek, Teisinger, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485206/
https://www.ncbi.nlm.nih.gov/pubmed/23119017
http://dx.doi.org/10.1371/journal.pone.0048437