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Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4(+)CD25(low/int) Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number

BACKGROUND: T cell-mediated liver damage is a key event in the pathogenesis of many chronic human liver diseases, such as liver transplant rejection, primary biliary cirrhosis, and sclerosing cholangitis. We and other groups have previously reported that galectin-9, one of the β-galactoside binding...

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Detalles Bibliográficos
Autores principales: Lv, Kun, Zhang, Yingying, Zhang, Mengying, Zhong, Min, Suo, Qifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485226/
https://www.ncbi.nlm.nih.gov/pubmed/23118999
http://dx.doi.org/10.1371/journal.pone.0048379