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Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4(+)CD25(low/int) Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number
BACKGROUND: T cell-mediated liver damage is a key event in the pathogenesis of many chronic human liver diseases, such as liver transplant rejection, primary biliary cirrhosis, and sclerosing cholangitis. We and other groups have previously reported that galectin-9, one of the β-galactoside binding...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485226/ https://www.ncbi.nlm.nih.gov/pubmed/23118999 http://dx.doi.org/10.1371/journal.pone.0048379 |