Cargando…
Structure-Based Engineering Increased the Catalytic Turnover Rate of a Novel Phenazine Prenyltransferase
Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto aromatic substrates in biosynthetic pathways of microbial secondary metabolites. Therefore, these enzymes contribute to the chemical diversity of natural products. Prenylation is frequently essential for the pharma...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485228/ https://www.ncbi.nlm.nih.gov/pubmed/23119011 http://dx.doi.org/10.1371/journal.pone.0048427 |