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RanBPM Is an Inhibitor of ERK Signaling

Ran-binding protein M (RanBPM) is a nucleocytoplasmic protein of yet unknown function. We have previously shown that RanBPM inhibits expression of the anti-apoptotic factor Bcl-2 and promotes apoptosis induced by DNA damage. Here we show that the effects of RanBPM on Bcl-2 expression occur through a...

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Detalles Bibliográficos
Autores principales: Atabakhsh, Elnaz, Schild-Poulter, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485245/
https://www.ncbi.nlm.nih.gov/pubmed/23118896
http://dx.doi.org/10.1371/journal.pone.0047803