Cargando…

Sequence Evolution of the Intrinsically Disordered and Globular Domains of a Model Viral Oncoprotein

In the present work, we have used the papillomavirus E7 oncoprotein to pursue structure-function and evolutionary studies that take into account intrinsic disorder and the conformational diversity of globular domains. The intrinsically disordered (E7N) and globular (E7C) domains of E7 show similar d...

Descripción completa

Detalles Bibliográficos
Autores principales: Chemes, Lucía B., Glavina, Juliana, Alonso, Leonardo G., Marino-Buslje, Cristina, de Prat-Gay, Gonzalo, Sánchez, Ignacio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485249/
https://www.ncbi.nlm.nih.gov/pubmed/23118886
http://dx.doi.org/10.1371/journal.pone.0047661