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Sequence Evolution of the Intrinsically Disordered and Globular Domains of a Model Viral Oncoprotein
In the present work, we have used the papillomavirus E7 oncoprotein to pursue structure-function and evolutionary studies that take into account intrinsic disorder and the conformational diversity of globular domains. The intrinsically disordered (E7N) and globular (E7C) domains of E7 show similar d...
Autores principales: | Chemes, Lucía B., Glavina, Juliana, Alonso, Leonardo G., Marino-Buslje, Cristina, de Prat-Gay, Gonzalo, Sánchez, Ignacio E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485249/ https://www.ncbi.nlm.nih.gov/pubmed/23118886 http://dx.doi.org/10.1371/journal.pone.0047661 |
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