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Regulatory T-Cells and Associated Pathways in Metastatic Renal Cell Carcinoma (mRCC) Patients Undergoing DC-Vaccination and Cytokine-Therapy

PURPOSE: To evaluate CD4(+)CD25(+)FOXP3(+) T regulatory cells (T(REG)) and associated immune-regulatory pathways in peripheral blood lymphocytes (PBL) of metastatic renal cell carcinoma (mRCC) patients and healthy volunteers. We subsequently investigated the effects of immunotherapy on circulating T...

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Detalles Bibliográficos
Autores principales: Schwarzer, Adrian, Wolf, Benita, Fisher, Jan L., Schwaab, Thomas, Olek, Sven, Baron, Udo, Tomlinson, Craig R., Seigne, John D., Crosby, Nancy A., Gui, Jiang, Hampton, Thomas H., Fadul, Camilo E., Heaney, John A., Ernstoff, Marc S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485261/
https://www.ncbi.nlm.nih.gov/pubmed/23118856
http://dx.doi.org/10.1371/journal.pone.0046600