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Fragmentation of SIV-gag Vaccine Induces Broader T Cell Responses
BACKGROUND: High mutation rates of human immunodeficiency virus (HIV) allows escape from T cell recognition preventing development of effective T cell vaccines. Vaccines that induce diverse T cell immune responses would help overcome this problem. Using SIV gag as a model vaccine, we investigated tw...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485275/ https://www.ncbi.nlm.nih.gov/pubmed/23118924 http://dx.doi.org/10.1371/journal.pone.0048038 |