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Fragmentation of SIV-gag Vaccine Induces Broader T Cell Responses

BACKGROUND: High mutation rates of human immunodeficiency virus (HIV) allows escape from T cell recognition preventing development of effective T cell vaccines. Vaccines that induce diverse T cell immune responses would help overcome this problem. Using SIV gag as a model vaccine, we investigated tw...

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Detalles Bibliográficos
Autores principales: Benlahrech, Adel, Meiser, Andrea, Herath, Shanthi, Papagatsias, Timos, Athanasopoulos, Takis, Li, Fucheng, Self, Steve, Bachy, Veronique, Hervouet, Catherine, Logan, Karen, Klavinskis, Linda, Dickson, George, Patterson, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485275/
https://www.ncbi.nlm.nih.gov/pubmed/23118924
http://dx.doi.org/10.1371/journal.pone.0048038

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