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PPARG Binding Landscapes in Macrophages Suggest a Genome-Wide Contribution of PU.1 to Divergent PPARG Binding in Human and Mouse

BACKGROUND: Genome-wide comparisons of transcription factor binding sites in different species can be used to evaluate evolutionary constraints that shape gene regulatory circuits and to understand how the interaction between transcription factors shapes their binding landscapes over evolution. RESU...

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Detalles Bibliográficos
Autores principales: Pott, Sebastian, Kamrani, Nima K., Bourque, Guillaume, Pettersson, Sven, Liu, Edison T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485280/
https://www.ncbi.nlm.nih.gov/pubmed/23118933
http://dx.doi.org/10.1371/journal.pone.0048102