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Non-Silent Story on Synonymous Sites in Voltage-Gated Ion Channel Genes
Synonymous mutations are usually referred to as “silent”, but increasing evidence shows that they are not neutral in a wide range of organisms. We looked into the relationship between synonymous codon usage bias and residue importance of voltage-gated ion channel proteins in mice, rats, and humans....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485311/ https://www.ncbi.nlm.nih.gov/pubmed/23119053 http://dx.doi.org/10.1371/journal.pone.0048541 |