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Intravenous Delivery of Targeted Liposomes to Amyloid-β Pathology in APP/PSEN1 Transgenic Mice

Extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles constitute the major neuropathological hallmarks of Alzheimer’s disease (AD). It is now apparent that parenchymal Aβ plaque deposition precedes behavioral signs of disease by several years. The development of agents that...

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Detalles Bibliográficos
Autores principales: Tanifum, Eric A., Dasgupta, Indrani, Srivastava, Mayank, Bhavane, Rohan C., Sun, Li, Berridge, John, Pourgarzham, Hoda, Kamath, Rashmi, Espinosa, Gabriela, Cook, Stephen C., Eriksen, Jason L., Annapragada, Ananth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485335/
https://www.ncbi.nlm.nih.gov/pubmed/23119043
http://dx.doi.org/10.1371/journal.pone.0048515