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Prostatic Acid Phosphatase Is Required for the Antinociceptive Effects of Thiamine and Benfotiamine

Thiamine (Vitamin B1) is an essential vitamin that must be obtained from the diet for proper neurological function. At higher doses, thiamine and benfotiamine (S-benzoylthiamine O-monophosphate, BT)–a phosphorylated derivative of thiamine–have antinociceptive effects in animals and humans, although...

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Detalles Bibliográficos
Autores principales: Hurt, Julie K., Coleman, Jennifer L., Fitzpatrick, Brendan J., Taylor-Blake, Bonnie, Bridges, Arlene S., Vihko, Pirkko, Zylka, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485352/
https://www.ncbi.nlm.nih.gov/pubmed/23119057
http://dx.doi.org/10.1371/journal.pone.0048562