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Slit2N/Robo1 Inhibit HIV-gp120-Induced Migration and Podosome Formation in Immature Dendritic Cells by Sequestering LSP1 and WASp

Cell-mediated transmission and dissemination of sexually-acquired human immunodeficiency virus 1 (HIV-1) in the host involves the migration of immature dendritic cells (iDCs). iDCs migrate in response to the HIV-1 envelope protein, gp120, and inhibiting such migration may limit the mucosal transmiss...

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Detalles Bibliográficos
Autores principales: Prasad, Anil, Kuzontkoski, Paula M., Shrivastava, Ashutosh, Zhu, Weiquan, Li, Dean Y., Groopman, Jerome E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485365/
https://www.ncbi.nlm.nih.gov/pubmed/23119100
http://dx.doi.org/10.1371/journal.pone.0048854