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Distinct and Overlapping Roles for AP-1 and GGAs Revealed by the “Knocksideways” System

Although adaptor protein complex 1 (AP-1) and Golgi-localized, γ ear-containing, ADP-ribosylation factor-binding proteins (GGAs) are both adaptors for clathrin-mediated intracellular trafficking, the pathways they mediate and their relationship to each other remain open questions [1]. To tease apart...

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Detalles Bibliográficos
Autores principales: Hirst, Jennifer, Borner, Georg H.H., Antrobus, Robin, Peden, Andrew A., Hodson, Nicola A., Sahlender, Daniela A., Robinson, Margaret S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485558/
https://www.ncbi.nlm.nih.gov/pubmed/22902756
http://dx.doi.org/10.1016/j.cub.2012.07.012