Cohesin’s DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation

Sister chromatid cohesion is mediated by entrapment of sister DNAs by a tripartite ring composed of cohesin’s Smc1, Smc3, and α-kleisin subunits. Cohesion requires acetylation of Smc3 by Eco1, whose role is to counteract an inhibitory (antiestablishment) activity associated with cohesin’s Wapl subun...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Kok-Lung, Roig, Maurici B., Hu, Bin, Beckouët, Frédéric, Metson, Jean, Nasmyth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485559/
https://www.ncbi.nlm.nih.gov/pubmed/22901742
http://dx.doi.org/10.1016/j.cell.2012.07.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485559/
https://www.ncbi.nlm.nih.gov/pubmed/22901742
http://dx.doi.org/10.1016/j.cell.2012.07.028

Ejemplares similares