Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile

Mice homozygous for several Tln2 gene targeted alleles are viable and fertile. Here we show that although the expression of talin2 protein is drastically reduced in muscle from these mice, other tissues continue to express talin2 albeit at reduced levels. We therefore generated a Tln2 allele lacking...

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Detalles Bibliográficos
Autores principales: Debrand, Emmanuel, Conti, Francesco J., Bate, Neil, Spence, Lorraine, Mazzeo, Daniela, Pritchard, Catrin A., Monkley, Susan J., Critchley, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485561/
https://www.ncbi.nlm.nih.gov/pubmed/22925892
http://dx.doi.org/10.1016/j.bbrc.2012.08.061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485561/
https://www.ncbi.nlm.nih.gov/pubmed/22925892
http://dx.doi.org/10.1016/j.bbrc.2012.08.061

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