Vav1 GEF activity is required for T cell mediated allograft rejection

The GDP exchange factor (GEF) Vav1 is a central signal transducer downstream of the T cell receptor and has been identified as a key factor for T cell activation in the context of allograft rejection. Vav1 has been shown to transduce signals both dependent and independent of its GEF function. The mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Haubert, Dirk, Li, Jianping, Saveliev, Alexander, Calzascia, Thomas, Sutter, Esther, Metzler, Barbara, Kaiser, Daniel, Tybulewicz, Victor L.J., Weckbecker, Gisbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485565/
https://www.ncbi.nlm.nih.gov/pubmed/22456277
http://dx.doi.org/10.1016/j.trim.2012.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485565/
https://www.ncbi.nlm.nih.gov/pubmed/22456277
http://dx.doi.org/10.1016/j.trim.2012.03.003

Ejemplares similares