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The PAKs come of age: Celebrating 18 years of discovery

Protein kinases are versatile signaling molecules that are involved in the regulation most physiological responses. The p21-activated kinases (PAKs) can be activated directly by the small GTPases Rac and Cdc42 and are among the best characterized downstream effectors of these Rho proteins. The struc...

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Detalles Bibliográficos
Autores principales: Field, Jeffrey, Manser, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485743/
https://www.ncbi.nlm.nih.gov/pubmed/23125949
http://dx.doi.org/10.4161/cl.22084