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PAK4–6 in cancer and neuronal development

PAKs 4, 5 and 6 are members of the group B family of p21-activated kinases. Among this group, PAK4 has been most extensively studied. While it has essential roles in embryonic development, in adults high levels of PAK4 are frequently associated with cancer. PAK4 is overexpressed in a variety of canc...

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Detalles Bibliográficos
Autor principal: Minden, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485745/
https://www.ncbi.nlm.nih.gov/pubmed/23125951
http://dx.doi.org/10.4161/cl.21171