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Sensitive Marker of the Cisplatin-DNA Interaction: X-Ray Photoelectron Spectroscopy of CL

The development of cisplatin and Pt-based analogues anticancer agents requires knowledge concerning the molecular mechanisms of interaction between such drugs with DNA. However, the binding dynamics and kinetics of cisplatin reactions with DNA determined by traditional approaches are far from satisf...

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Detalles Bibliográficos
Autores principales: Xiao, Fangxing, Yao, Xiaobin, Bao, Qianhong, Li, Danzhen, Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485869/
https://www.ncbi.nlm.nih.gov/pubmed/23133406
http://dx.doi.org/10.1155/2012/649640