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Inhibition of Osteoclast Generation: A Novel Function of the Bone Morphogenetic Protein 7/Osteogenic Protein 1

Monocytes have the potential to differentiate to either macrophages, dendritic cells, or to osteoclasts. The microenvironment, particularly cytokines, directs the monocyte differentiation. Receptors of NFκB (RANK) ligand, tumor necrosis factor (TNF) α, or interleukin- (IL-) 8 have be identified as i...

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Detalles Bibliográficos
Autores principales: Maurer, Thomas, Zimmermann, Gerald, Maurer, Susanne, Stegmaier, Sabine, Wagner, Christof, Hänsch, G. Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486172/
https://www.ncbi.nlm.nih.gov/pubmed/23132958
http://dx.doi.org/10.1155/2012/171209