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In Vitro and In Vivo Characterizations of Chiglitazar, a Newly Identified PPAR Pan-Agonist

Solid rationales are still present for the identification of synthetic ligands to simultaneously target multiple PPAR subtypes for the treatment of T2DM. The purpose of this study was to characterize the in vitro and in vivo differential effects of chiglitazar, a non-TZD type of PPAR pan-agonist cur...

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Detalles Bibliográficos
Autores principales: He, B. K., Ning, Z. Q., Li, Z. B., Shan, S., Pan, D. S., Ko, B. C. B., Li, P. P., Shen, Z. F., Dou, G. F., Zhang, B. L., Lu, X. P., Gao, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486420/
https://www.ncbi.nlm.nih.gov/pubmed/23150725
http://dx.doi.org/10.1155/2012/546548