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Identification of Small Molecules That Suppress Ricin-Induced Stress-Activated Signaling Pathways
Ricin is a member of the ribosome-inactivating protein (RIP) family of plant and bacterial toxins. In this study we used a high-throughput, cell-based assay to screen more than 118,000 compounds from diverse chemical libraries for molecules that reduced ricin-induced cell death. We describe three co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486792/ https://www.ncbi.nlm.nih.gov/pubmed/23133670 http://dx.doi.org/10.1371/journal.pone.0049075 |