Pharmacokinetic Properties of 2(nd)-Generation Fibroblast Growth Factor-1 Mutants for Therapeutic Application

Fibroblast growth factor-1 (FGF-1) is an angiogenic factor with therapeutic potential for the treatment of ischemic disease. FGF-1 has low intrinsic thermostability and is characteristically formulated with heparin as a stabilizing agent. Heparin, however, adds a number of undesirable properties tha...

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Detalles Bibliográficos
Autores principales: Xia, Xue, Babcock, Joseph P., Blaber, Sachiko I., Harper, Kathleen M., Blaber, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486806/
https://www.ncbi.nlm.nih.gov/pubmed/23133616
http://dx.doi.org/10.1371/journal.pone.0048210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486806/
https://www.ncbi.nlm.nih.gov/pubmed/23133616
http://dx.doi.org/10.1371/journal.pone.0048210

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