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Serum concentrations of nitrite and malondialdehyde as markers of oxidative stress in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors

BACKGROUND: Chronic myeloid leukemia is a neoplasm characterized by clonal expansion of hematopoietic progenitor cells resulting from the (9:22)(q34,11) translocation. The tyrosine kinase abl fusion protein,the initial leukemogenic event in chronic myeloid leukemia, is constitutively activated thus...

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Detalles Bibliográficos
Autores principales: Petrola, Maria Juracy, de Castro, Alana Joselina Montenegro, Pitombeira, Maria Helena da Silva, Barbosa, Maritza Cavalcante, Quixadá, Acy Telles de Souza, Duarte, Fernando Barroso, Gonçalves, Romelia Pinheiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Hematologia e Hemoterapia 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486825/
https://www.ncbi.nlm.nih.gov/pubmed/23125543
http://dx.doi.org/10.5581/1516-8484.20120091