Stimulation of Gross Chromosomal Rearrangements by the Human CEB1 and CEB25 Minisatellites in Saccharomyces cerevisiae Depends on G-Quadruplexes or Cdc13

Genomes contain tandem repeats that are at risk of internal rearrangements and a threat to genome integrity. Here, we investigated the behavior of the human subtelomeric minisatellites HRAS1, CEB1, and CEB25 in Saccharomyces cerevisiae. In mitotically growing wild-type cells, these GC–rich tandem ar...

Descripción completa

Detalles Bibliográficos
Autores principales: Piazza, Aurèle, Serero, Alexandre, Boulé, Jean-Baptiste, Legoix-Né, Patricia, Lopes, Judith, Nicolas, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486850/
https://www.ncbi.nlm.nih.gov/pubmed/23133402
http://dx.doi.org/10.1371/journal.pgen.1003033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486850/
https://www.ncbi.nlm.nih.gov/pubmed/23133402
http://dx.doi.org/10.1371/journal.pgen.1003033

Ejemplares similares