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Stimulation of Gross Chromosomal Rearrangements by the Human CEB1 and CEB25 Minisatellites in Saccharomyces cerevisiae Depends on G-Quadruplexes or Cdc13

Genomes contain tandem repeats that are at risk of internal rearrangements and a threat to genome integrity. Here, we investigated the behavior of the human subtelomeric minisatellites HRAS1, CEB1, and CEB25 in Saccharomyces cerevisiae. In mitotically growing wild-type cells, these GC–rich tandem ar...

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Detalles Bibliográficos
Autores principales:	Piazza, Aurèle, Serero, Alexandre, Boulé, Jean-Baptiste, Legoix-Né, Patricia, Lopes, Judith, Nicolas, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486850/ https://www.ncbi.nlm.nih.gov/pubmed/23133402 http://dx.doi.org/10.1371/journal.pgen.1003033

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